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FIP Treatment

10 de jul. de 2024

 

When a cat gets FIP, it is progressive and almost always fatal. Even so, many people have successfully treated their kitty, you can too!

There are two compounds that have been researched against the FIP, one is called GC376 and the other is called GS441524, these two drugs with completely different principles, both of which inhibit the replication of FCoV.

Up to now, a large number of transmissible belly cats have been treated and discontinued by these two drugs. However, GS-441524 was found to cross the blood-eye barrier, blood-brain barrier to reach the eye, and the central nervous system. Compared to GC376, which treated only 6 out of 20 cats that remained disease-free after more than 18 months, GS-441524 was significantly more effective, using fewer doses and shorter treatment time.

1. Reactions after starting with GS

The fever usually goes down within 72 hours.

Fluid build-up begins to subside within 7 to 30 days. Each cat is different.

Appetite will gradually return and bowel movements will gradually resume.

Mental state will gradually recover.

About three or four weeks, the cat with diarrhea will be no different from a normal healthy cat, but we should not take it lightly, and don't think that the disease has been cured just because the cat has recovered.

Once again, the treatment takes some time, and whether it is effective or not, we should look at the state of the cat in the early stage and the indicators in the later stage.

2. Review

Review time: During the treatment period, it is recommended that a review be conducted every 4-6 weeks, including routine blood tests, biochemistry, SAA, etc.

The chemistry panel should include at minimum glucose, creatinine, BUN, albumin, globulin, ALT, ALP and total bilirubin

3. Stopping the treatment

Step 1 (check stage):

After 84 days of medicine and cats in the situation as well as completely normal for more than a week, you can take the cat to do the examination (mainly blood, biochemical testing, SAA).

Step 2 (whether stopping the treatment):

Situation 1: If the A/G of 0.7 or more (better is 0.8 or more), SAA is normal. At this point in 10-15 days 441 can be stopped directly (can be soft stopping the injection so that the cat has a process of getting used to), it is recommended to leave 3 injections of meds has been done as a precautionary measure in case of relapse.

Situation 2: If the A/G is still below 0.8 (SAA, and blood routine at the moment to see normal cats appear very small problem, 99% are white ball ratio does not meet the standard), but also to continue to inject for 15 days, then do the examination. If you reach the index of stopping the needle, enter the situation 1 phase of stopping the needle, if it is still not normal is divided into two cases:

1) Situation 2.1: The cat's A/G has risen by a long time, usually more than 0.5 increase, but also continue to continue the injection according to Situation 2.

2) Situation 2.2: The difference between the cat's A/G and the previous one is very small ± 0.2, at this time, you can also consider stopping the treatment, and follow the Situation 1.

All of the above is for reference only, the specific situation needs to be judged according to the cat's condition. As you go through treatment, stay in contact with your vet and/or treatment advisor -- they cannot advise you about things they don't know about.

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